Episode 032: Morley Robbins, Iron and Magnesium Revisited, What is Really Being Taught in Medical School?
In Episode 032 of A Medicinal Mind: Wisdom and Well Being I welcome back visionary researcher and the man behind the Magnesium Advocacy Group: Morley Robbins. From start to finish, this conversation is another whirlwind of mineral metabolism, our second dive back into the fascinating world of magnesium, iron and copper.
In this conversation, Morley quickly get us up to speed on iron and its primary role in the body as the structural center of the oxygen carrying molecule hemoglobin, and then quickly pushes us forward into a fascinating exploration of blood and the red blood cell.
What do we mean when we say blood?
How many red blood cells do we really have?
Where do they come from and what is their primary role?
Where does iron and oxidative stress enter the picture?
We then discuss a surprising discovery by Morley, an iron metabolism and pathology module from very own medical school!
Together we deconstruct what I was taught as a second year medical student and perhaps the pieces of the story that were missing from my education.
Morley then leads us into a discussion of the reticuloendothelial system and the life cycle of a red blood cell. What role does iron, and magnesium play in the function and shape of our red blood cells? Are our cells living as long as they should? What can we learn from sickle cell anemia and other disorders of the red blood cell membrane when it comes to iron and magnesium metabolism?
Changing gears, Morley gives us a wonderful description of our primary energy production system: the electron transport chain, the role of reactive oxygen scavengers and anti-oxidants, and the interplay of copper and magnesium to produce energy and ultimately protect us from free radical damage.
We end the discussion with a little thought experiment exploring the implications of iron fortification and compare the amounts and forms of iron found in animal foods vs fortified cereals. We trace the journey of excessive and poorly absorbed iron into our colon, exploring the resulting gut dysbiosis and immune activation that can ensue from this excessive oxidative load.
Morley gives us hope at the end of this discussion as he describes his food based root cause protocol designed to restore the intricate balance of these minerals in our bodies.
Morley’s curiosity is unparalleled and I am thankful for his desire to research deas at the edge of science, sharing his findings with us all.
I encourage you to spend some time with this conversation, as you will likely need to listen 2, 3 or 4 times to pick up all the insights and wisdom discussed.
And lastly, If you enjoyed this conversation, we would really appreciate it if you would take 2 minutes to leave a review in I-Tunes so more people can find our podcast and its curious explorations.
And with that let’s dig into the show!
ERRATA: In the podcast I mistakenly describe hereditary spherocytosis as a primary issue of hemoglobin. It is not an primary issue with hemoglobin but an issue with red blood cell membrane proteins. Sickle cell anemia is a primary hemoglobinopathy or issue with hemoglobin that results in deformation of the red blood cell membrane, causing the cells to appear sicked in shapre. I apologize for the error in the podcast and hope you find this explanation helpful.
Catch up with our last episode with Morley using this link:
University of Virginia School of Medicine Iron Metabolism Module: Dr. Innes, MD
Got Mag: http://gotmag.org
Root Cause Protocol: http://gotmag.org/the-root-cause-protocol/
Episode 031: Benjamin Richardson, A Citizen Scientist’s View on Healthspan, the Fasting Mimicking Diet and Self Experimentation
In episode 031 of A Medicinal Mind: Wisdom and Well Being, I explore the world of self experimentation, longevity, intermittent fasting and fasting mimicking diets with citizen scientist Benjamin Richardson.
I recently stumbled across Ben’s work and page at Forever Free From during one of my many rabbit hole forays into emerging medical therapies, this time into the world of intermittent fasting and the newly evolving 5 day Fasting Mimicking Diet.
In this conversation, Benjamin and I delve into some of his curious self experiments, implementing major dietary and lifestyle changes, quantifying the results and sharing this wisdom with a wider audience.
We explore questions such as
What is the difference between lifespan vs. healthspan?
What really is behind the aging process and who is at the cutting edge of longevity research?
Benjamin than leads us into a thoughtful discussion of fasting, outline the differences between intermittent fasting, time restricted eating windows and the Fasting Mimicking Diet or FMD.
He shares he own story researching, planning and implementing the 5 day FMD as well as his generous reflections and resources created so that others can try the dietary approach for themselves.
Through it all, Benjamin shares his authentic curiosity and his genuine desire to help others through his own experimentation.
Dietary interventions such the FMD and intermittent fasting are emerging as powerful therapies for neurocognitive illnesses such as Alzheimer's dementia as well as for metabolic disorders such as diabetes and even cancer and it is quite exciting to explore this space with such a passionate and knowledgeable friend.
Benjamin has provided a wealth of curated resources available on the podcast page and I encourage you to explore some this nourishing content as well as the resources on his own page at foreverfreefrom.com.
We will certainly be having Benjamin back soon to discuss his most recent experiment involving glucose monitoring, carb tolerance, insulin resistance and heart rate variability.
I really hope you enjoy the show!
Keep up to date with all of Ben's exciting news using the links below:
Ben’s page Forever Free From
Fasting Mimicking Diet Resources
DIY Guide to FMD including template
Resource: Guide to science of Fasting https://endpoints.elysiumhealth.com/the-science-of-fasting-2f5b56a2a65d
Resource: Fasting Mimicking Diet First Human Trial outcomes review
Resource: Commercial ProLon version of FMD
Resource: Blue Zones actionable insights based on research on the world’s longest lived communities
Resource: Dr Rhonda Patrick interview with Salk Institute Dr Satchin Panda on Time Restricted Feeding
Resource: Dr Rhonda Patrick interview with Buck Institute Dr Eric Verdin on
Resource: Dr Rhonda Patrick interview with Valter Longo on Fasting Mimicking Diet (FMD)
Resource: Buck Institute Science of Aging Blog
Resource: Homepage of Chris Kresser, functional medicine advocate, practitioner and author of Your Personal Paleo Code and Paleo Cure
New Post on Carb Experimenting: Testing Blood Sugar DIY